- HADDOCK (High Ambiguity Driven protein-protein DOCKing) is an information-driven flexible docking approach for the modeling of biomolecular complexes. HADDOCK distinguishes itself from ab-initio docking methods in the fact that it encodes information from identified or predicted protein interfaces in ambiguous interaction restraints (AIRs) to drive the docking process. HADDOCK can deal with a large class of modeling problems including protein-protein, protein-nucleic acids and protein-ligand complexes.
- More information about HADDOCK can be found on the HADDOCK website
- HADDOCK webserver
- To use the HADDOCK docking server you must have registered for an account. If you do not have a account yet you can register here
-
- HADDOCK server: the Expert interface (requires Expert level access)
- HADDOCK server: the Refinement interface (requires Expert level access)
- HADDOCK server: the Guru interface (requires Guru level access)
- HADDOCK server: the Multi-body interface (requires Guru level access)
The default HADDOCK settings used by the server can be found here
A list of modified amino acids supported by HADDOCK can be found here
- HADDOCK webserver statistics
- Server statistics generated on: 2010-03-11 03:05:04
- Number of running requests: 6 , of which 0 on the eNMR grid
- Number of queued requests: 1
- Total number of served requests as of June 1st 2008:
7356
,
of which 373 on the eNMR grid - Number of registered users: 687 ( 517 easy / 75 expert / 95 guru)
- Server example
- An example of the server output for the e2a-hpr example provided with the HADDOCK distribution
can be found here. This is the result of a run
via the "easy interface" using only chemical shift perturbations as defined in the
HADDOCK tutorial.
- Tutorials
- A demo web form for the easy interface with pre-loaded parameters is available here
A demo web form for the guru interface with pre-loaded parameters is available here
A tutorial describing the use of the HADDOCK web portal with various combinations of data is available here
A tutorial movie is available here (requires Flash)
